Comprehensive management of arteriovenous malformations of the brain and spine edited by robert f spetzler douglas s kondziolka randall t higashida m yashar s kalani online isbn 9781139523943. Comprehensive management of arteriovenous malformations of the brain and spine spetzler robert f kondziolka douglas s higashida randall t kalani m yashar . Vascular malformations of the brain and spine pose many management challenges this text provides a comprehensive state of the art review of the natural history treatment options and outcomes of patients with these conditions despite their relative rarity these lesions are responsible for devastating injury to individuals and can cause an enduring physical psychological and economic . Vascular malformations of the brain and spine pose many management challenges this text provides a comprehensive state of the art review of the natural history treatment options and outcomes of patients with these conditions despite their relative rarity these lesions are responsible for devastating injury to individuals and can cause an